Non-coding antisense RNA can be used to stimulate protein production Date: October 16, 2012 Source: RIKEN Summary: While studying Parkinson's disease, an international research group made a ...

The antisense fragment has the function of a "lock" into which the key of the coding RNA specific for that gene is inserted, while the other one has a stimulating function on protein synthesis." ...

Gene silencing by RNA interference (RNAi) has become a powerful tool for functional genomics. In the January 25 Science, Tijsterman et al. report a gene-silencing method induced by short (25 ...

Much of the non-coding RNA is produced as the complementary strand to mRNA and is therefore referred to as antisense RNA (asRNA). Their function has been unclear for a long time.

GGGGCC repeats in the C9ORF72 gene, sometimes numbering in the thousands, are the most common genetic cause of ALS and FTD (see Sep 2011 news). Both sense and antisense transcripts containing these ...

For at least 30 years scientists and drug developers bent on a sorely needed new class of therapeutics have been studying antisense RNA. The concept is deceptively simple: Binding of an ...

Antisense oligonucleotide (ASO)—a class of drugs that works by targeting RNA to alter gene expression and control aberrant proteins in ways that traditional drugs can’t.

Antisense RNA has emerged as an important type of inhibitor of HIV gene expression, 14 18 19 and one in vivo study, where macaques whose T lymphocytes had been transduced with antisense-expressing ...

In a paper recently uploaded to the bioRxiv* preprint server, structure-based ASOs are developed against SARS-CoV-2, intended to bond with RNA in its structured in situ form, rather than the more ...

The antisense fragment has the function of a "lock" into which the key of the coding RNA specific for that gene is inserted, while the other one has a stimulating function on protein synthesis." ...

The antisense fragment has the function of a 'lock' into which the key of the coding RNA specific for that gene is inserted, while the other one has a stimulating function on protein synthesis." ...