Non-coding antisense RNA can be used to stimulate protein production Date: October 16, 2012 Source: RIKEN Summary: While studying Parkinson's disease, an international research group made a ...

The antisense fragment has the function of a "lock" into which the key of the coding RNA specific for that gene is inserted, while the other one has a stimulating function on protein synthesis." ...

Gene therapy appears to be a promising approach for a subset of genetic deafness, although challenges remain with development ...

GGGGCC repeats in the C9ORF72 gene, sometimes numbering in the thousands, are the most common genetic cause of ALS and FTD (see Sep 2011 news). Both sense and antisense transcripts containing these ...

Gene silencing by RNA interference (RNAi) has become a powerful tool for functional genomics. In the January 25 Science, Tijsterman et al. report a gene-silencing method induced by short (25 ...

Antisense RNA has emerged as an important type of inhibitor of HIV gene expression, 14 18 19 and one in vivo study, where macaques whose T lymphocytes had been transduced with antisense-expressing ...

Depending on where they are designed to bind, these antisense molecules can prevent an RNA from being translated into a protein, which reduces levels of that protein in the body or brain.

Experiences with two other RNA-based therapeutic strategies, antisense RNA and ribozymes, illustrate the daunting obstacles that stand in the way of the therapeutic application of RNAi.

The antisense fragment has the function of a "lock" into which the key of the coding RNA specific for that gene is inserted, while the other one has a stimulating function on protein synthesis." ...

The antisense fragment has the function of a 'lock' into which the key of the coding RNA specific for that gene is inserted, while the other one has a stimulating function on protein synthesis." ...