New imaging tools reveal how within an hour of infection, the virus begins to alter our chromosomes to kick-start its own replication.

Got junk? Learn how a new study suggests that, when it comes to our genetic code, that may actually be a good thing.

The cold sore-causing Herpes Simplex Virus (HSV-1) hijacks human cells and reconfigures its DNA within just an hour after infection, according to a new study that may help tackle the pathogen.

By triggering the DNA damage response in a patient, this could dramatically slow viral DNA replication, suppressing the infection, providing us with a novel avenue for possible antiviral treatments of ...

A common hallmark of viral genome replication is a high mutation rate, which can aid in their ability to evade new treatments and acquire resistance to once-effective antiviral medications.

"If we think of viral replication as an old-fashioned milk assembly line, we know how the milk bottles are formed and that they come out filled, but prior to this study, the process of filling ...

Recall that DNA-dependent RNA polymerases usually take DNA as a template and convert it into one or another form of RNA. Hepatitis D virus, however, is made up exclusively of RNA.

In contrast, when a virus hijacks a host cell's DNA replication machinery, it replicates hundreds of times. This "unlicensed" replication is not subject to the same quality control and is much ...

In contrast, when a virus hijacks a host cell's DNA replication machinery, it replicates hundreds of times. This "unlicensed" replication is not subject to the same quality control and is much ...

Developing a method that can quickly and easily generate replication-defective live-attenuated viruses, the researchers said, will accelerate vaccine development for diseases caused by DNA viruses.

Hepatitis B virus, a killer of more than one million people each year, is a notoriously wily virus, often lingering and ...