Radiation damage remains the principal limitation in achieving higher resolution in cryo-electron microscopy (cryo-EM), ...

Atomic-scale imaging emerged in the mid-1950s and has been advancing rapidly ever since—so much so, that back in 2008, physicists successfully used an electron microscope to image a single ...

Electron Source Much like the traditional scanning electron microscope (SEM), the field emission scanning electron microscope uses electrons to illuminate a sample, instead of visible light as is used ...

While the original electron microscope arrived in the early 1930’s (there’s still a controversy to this day over who invented the very first one), scientists have relied on what are known as ...

We provide structured training for both newcomers and users with previous experience in single-particle electron microscopy analysis. We review electron microscope safety, negative staining, carbon ...

Since they came into use in 1938, electron microscopes have played a pivotal role in a host of scientific advances, including the discovery of new proteins and therapeutics and contributions made to ...

Image Credit: Laser Quantum Ltd A Brief Introduction to SEM and TEM It is important to discuss the main working principles of EM before outlining the principles of time-resolved electron microscopy.

Cryogenic-electron microscopy (cryo-EM) has rapidly become one of the most important experimental methods in structural biology and nanoscience. In this article, AZoNano discusses the working ...

Detection of either kind of electron allows for reconstruction of the size of the imaged object as well as visualization of any more complex structural features. Cryo-electron microscopy (cryo-EM) ...

Researchers at Forschungszentrum Jülich and Heinrich Heine University Düsseldorf led by Prof. Dr. Carsten Sachse are using cryo-electron microscopy, or cryo-EM for short, to make biomolecules ...