Antisense RNA has emerged as an important type of inhibitor of HIV gene expression, 14 18 19 and one in vivo study, where macaques whose T lymphocytes had been transduced with antisense-expressing ...

The antisense fragment has the function of a "lock" into which the key of the coding RNA specific for that gene is inserted, while the other one has a stimulating function on protein synthesis." ...

RNA interference provides powerful tools for controlling gene expression in cultured cells. Whether RNAi will provide similarly powerful drugs is unknown. Lessons from development of antisense ...

Scientists at Johns Hopkins have discovered how a natural RNA molecule can block HIV from reactivating, opening doors to a ...

GGGGCC repeats in the C9ORF72 gene, sometimes numbering in the thousands, are the most common genetic cause of ALS and FTD (see Sep 2011 news). Both sense and antisense transcripts containing these ...

AntiClastic™ Antisense Oligonucleotide (AntiClastic ASO) is a proprietary platform available exclusively through partnerships with Alloy. Sudhir Agrawal, D.Phil, inventor of the underlying IP ...

Antisense oligonucleotide (ASO)—a class of drugs that works by targeting RNA to alter gene expression and control aberrant proteins in ways that traditional drugs can’t.

The antisense fragment has the function of a "lock" into which the key of the coding RNA specific for that gene is inserted, while the other one has a stimulating function on protein synthesis." ...

Post this Alloy’s AntiClastic Antisense platform allows drug developers to realize the true potential of antisense therapeutics by reaching intracellular disease targets at the RNA level.

Gene silencing by RNA interference (RNAi) has become a powerful tool for functional genomics. In the January 25 Science, Tijsterman et al. report a gene-silencing method induced by short (25 ...

Non-coding antisense RNA can be used to stimulate protein production Date: October 16, 2012 Source: RIKEN Summary: While studying Parkinson's disease, an international research group made a ...

The antisense fragment has the function of a 'lock' into which the key of the coding RNA specific for that gene is inserted, while the other one has a stimulating function on protein synthesis." ...