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HSV-1 co-opts two genes — RNA polymerase II (RNAP 2) and DNA topoisomerase (TOP1) — that compact the host’s chromatin into super-dense bundles. Chromatin is the DNA-protein complex that, when ...
Plant RNA viruses pose a significant threat to global agriculture, affecting a vast array of crop species and leading to ...
This important study explores the role of SIRT2 in regulating Japanese encephalitis virus replication and disease progression in rodent models. The findings presented are novel as sirtuins are known ...
New research has discovered that the Herpes virus actually takes control of key RNA functionality and changes human DNA in ...
If we don’t invest in technologies like mRNA vaccines for pandemic influenza now, once a virus starts going human-to-human, ...
In the shadows of Python Cave, Uganda, a leopard leaps from a guano mound—formed by bat excrement—and sinks its teeth into a ...
Background Chronic inflammation and elevated reactive oxygen species are key contributors to hepatocellular carcinoma (HCC) ...
Almost all cervical cancers are caused by human papillomaviruses (HPVs). In most cases, HPV DNA is integrated into the human genome. We found that tumor-specific, HPV-human DNA junctions are ...
SARS-CoV-2 is a positive-sense single-stranded RNA virus. It is contagious in humans and is the cause of the coronavirus disease 2019 (COVID-19). Vaccination-induced antibody responses wane, but ...