Isaac Paredes appeared to injure his right leg while running to first base another in a season full of injuries for Houston.

Paredes was pulled from Saturday's game versus Seattle due to right hamstring discomfort, Matt Kawahara of the Houston Chronicle reports.

The Houston Astros and the Seattle Mariners play the middle contest of a 3-game series Saturday at T-Mobile Park in Seattle.

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Mariners fourth. Julio Rodriguez walks. Cal Raleigh pops out to Christian Walker. Julio Rodriguez doubled off first. Randy Arozarena homers to center field. Donovan Solano strikes out swinging.

Houston Astros (56-41, first in the AL West) vs. Seattle Mariners (52-45, second in the AL West) Seattle; Saturday, 9:40 p.m.