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Genetic determinants of host- and virus-derived insertions for hepatitis E virus replication. Nature Communications, 2024; 15 (1) DOI: 10.1038/s41467-024-49219-8 ...
The other possibility is that the quasi-double stranded secondary structure of hepatitis D virus —a result of 70% sequence self-complementarity — is mistaken for DNA, thereby hijacking RNA ...
Previous research has shown that HIV-specific CD8 T-cell responses directed against five genetically conserved HIV-1 protein ...
Although outbreaks of Ebola virus are rare, the disease is severe and often fatal, with few treatment options. Rather than ...
Collectively, the current research sheds light on a potential alternative pathway for targeting and limiting CoV replication through host non-coding RNA, i.e., miRNAs, that target RdRp enzymatic ...
More information: Zaikun Xu et al, The Wnt/β-catenin pathway is important for replication of SARS-CoV-2 and other pathogenic RNA viruses, npj Viruses (2024). DOI: 10.1038/s44298-024-00018-4 ...
The enzyme methyltransferase MTr1 provides the cap structure of cellular RNA. Prof. Kato's team found out how much influenza viruses depend on the activity of this enzyme for their replication and ...
New imaging tools reveal how within an hour of infection, the virus begins to alter our chromosomes to kick-start its own replication.
Hepatitis B virus, a killer of more than one million people each year, is a notoriously wily virus, often lingering and ...
Scientists report that a class of drugs, called RNA interference (RNAi) therapeutics, represent a major advancement in the ...