Patients with chronic low back pain may exhibit worsened cognitive function compared with pain-free individuals.

Bedtime TNX-102 SL was safe and effective for the treatment of fibromyalgia by improving symptoms of pain, disrupted sleep, and fatigue.

Upadacitinib demonstrated greater clinical efficacy and a comparable safety profile to adalimumab for treating RA, regardless of patients’ baseline CV risks.

For adults with NLUTD or IC/BPS, robot-assisted laparoscopic supratrigonal cystectomy with augmentation cystoplasty is feasible.

Cannabis use disorder is associated with increased risk of benign salivary gland tumors, according to study findings.

From 2008 to 2023, there was an increase in the prevalence of extremely severe obesity in children, especially among older adolescents and non-Hispanic Black children.

Higher UPF-consumption was linked to worse knee OA outcomes among women, including higher pain scores, worse physical function, and thinner knee cartilage.

Urgent care visits are often associated with inappropriate prescriptions of antibiotics, glucocorticoids, and opioids.

Among patients with T2D and DPN, some with nonpainful DPN developed neuropathic pain over a 5-year period while others with painful DPN experienced relief.

SGLT2 inhibitors, compared with GLP-1 RAs, were associated with lower risks for osteoarthritis and joint replacement surgery among patients with T2D.

Truncal vagotomy was linked to an increased risk for RA, while neither truncal nor superselective vagotomy were associated with increased OA risk.

Treatments for bronchiectasis, chronic immune thrombocytopenia, fibromyalgia, Friedreich ataxia, and recurrent respiratory papillomatosis are under review.