Scientists have created an artificial RNA system that can copy itself using simple building blocks and temperature changes.

Maintaining high transcriptional fidelity is essential to life. For all eukaryotic organisms, RNA polymerase II (Pol II) is responsible for messenger RNA synthesis from the DNA template. Three key ...

In this study, a whole-course nucleic-acid-constructed biosensor that combines the all-in-one concepts of the universal blocking linker recombinase polymerase amplification (UBLRPA) and a peptide ...

A new study reveals that blocking ribosomal RNA production rewires cancer cell behavior and could help treat genetically ...

The tumor suppressor p53 is a transcription factor that controls the expression of hundreds of genes. Emerging evidence suggests that the p53-induced RNA-binding protein ZMAT3 is a key splicing ...

The growing incidence of infectious diseases, cancer, and chronic illnesses has substantially increased the demand for ...

Viruses are entirely dependent on their hosts to reproduce. They ransack living cells for parts and energy and hijack the ...

Researchers at the Johns Hopkins Kimmel Cancer Center and Department of Radiation Oncology and Molecular Radiation Sciences uncovered a new tumor-suppressive response that could lead to novel ...

Researchers at the Johns Hopkins Kimmel Cancer Center and Department of Radiation Oncology and Molecular Radiation Sciences uncovered a new tumor-suppressive response that could lead to novel ...

President and COO Judy Murrah Appointed New Chairperson of the Board of Directors and CEO STONY BROOK, NY / ACCESS Newswire / June 17, 2025 / Applied DNA Sciences, Inc. (NASDAQ:APDN) (“Applied DNA” or ...

Laiho holds patents on RNA polymerase 1 inhibitors, which are managed by The Johns Hopkins University in accordance with its conflict-of-interest policies.

To quantitatively assess MSI, we evaluated the length of MSI peak shifts from polymerase chain reaction-based fragment length data in two cohorts (combined N = 237) of hereditary (Lynch syndrome) and ...