Cambridge, Massachusetts-based Envisagenics focuses on using AI to analyse errors in RNA splicing, a process in which a precursor form of messenger RNA (mRNA) – which is used as a template for ...

"By targeting key processes like RNA splicing and modification ... from my lab and merge them with Leslie's powerful and robust model systems to nail down this novel mechanism," said co ...

In myotonic dystrophic patients, titration of MBNL protein by RNA containing expanded CUG repeats leads to expression of a fetal splicing form of the cardiac sodium channel, SCN5A, inappropriate ...

The realization that most human genes generate multiple mRNAs encoding divergent protein isoforms via alternative splicing and polyadenylation has revealed extensive regulation that remains to be ...

Christine Guthrie, a molecular geneticist whose studies of eukaryotic RNA yielded crucial insights into the workings of pre-mRNA splicing, the process by which introns are removed to produce mature ...

In this webinar, Dr. Megan L Noonan will present her research on the role of alternative splicing in kidney disease progression, discussing how she used nanopore RNA sequencing to accurately detect ...